An international financial organization must ensure their highly transactional application's operations can withstand the outage of a data center without any service interruption. Furthermore, the application should incur minimal latency for users in Europe, North America, and Asia. Considering cost-effectiveness and operational complexity, what deployment approach adheres BEST to these requirements?
Deploy the application into a single AWS Region and distribute it across multiple Availability Zones, leveraging Amazon Route 53 health checks for failover.
Implement a global database cluster with cross-region read replicas to ensure the application’s relational data remains available and experiences low latency accesses.
Utilize one AWS Region to host the primary instance and establish cross-region read replicas in regions closest to Europe, North America, and Asia.
Establish the application in multiple AWS Regions each located near Europe, North America, and Asia, with an Amazon Route 53 latency-based routing policy.