The correct answer is Compliance with national laws and regulations, as it directly relates to the obligations an organization has to adhere to the legal framework set forth by the government of the country in which it operates. Non-compliance can result in legal actions, fines, or sanctions against the organization. Local business norms are relevant to cultural practices but do not hold regulatory authority. Regional trends may influence business strategy but lack the legal impact of national laws. Global standards are best practices that might be adopted internationally, yet they do not replace national legal requirements.