Which urine collection method is most commonly recommended for a routine urinalysis because it minimizes contamination from microorganisms and cells located in the distal urethra?
First-void (initial stream) specimen
Catheterized specimen
Midstream clean-catch specimen
24-hour timed collection
A properly collected midstream clean-catch specimen reduces contamination by discarding the first portion of urine (which may contain urethral flora) and collecting the midstream portion in a sterile container. This technique yields a sample that better represents the contents of the bladder. A first-void specimen contains more contaminants, a 24-hour timed collection is used for quantitative analyses, and a catheterized specimen is generally reserved for patients who cannot void or when a sterile specimen is required but is more invasive.
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