Which medication is generally considered safest for use as an analgesic in an obstetrical patient during the first trimester of pregnancy?
Diclofenac
Fentanyl
Acetaminophen
Ibuprofen
Acetaminophen is generally considered the safest analgesic for use during the first trimester of pregnancy because it does not have significant adverse effects on fetal development. Nonsteroidal anti-inflammatory drugs (NSAIDs) like Ibuprofen and Diclofenac are generally avoided due to risks, such as potential closure of the fetal ductus arteriosus and other complications. Fentanyl, while a potent analgesic, is a narcotic and should be used cautiously as it can affect both the mother and the fetus.
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