Which of the following is considered the definitive first-line therapy for an episode of acute uncomplicated bacterial cystitis in an otherwise healthy adult patient who is not pregnant?
Increased fluid intake without medication
Daily cranberry extract supplementation alone
Topical vaginal estrogen therapy alone
A 3- to 5-day course of an appropriate oral antibiotic
Acute uncomplicated cystitis is caused by bacterial infection of the bladder, most commonly Escherichia coli. National and international guidelines recommend a short course of an appropriate oral antibiotic (e.g., nitrofurantoin for 5 days, trimethoprim-sulfamethoxazole for 3 days, or a single dose of fosfomycin) as first-line treatment. Adequate hydration, cranberry products, or topical estrogen may help prevent future infections, but they do not eradicate an active infection on their own. Therefore, antibiotic therapy is essential to resolve the infection and prevent complications such as pyelonephritis.
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Why are short courses of antibiotics effective for acute uncomplicated cystitis?
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How do antibiotics like nitrofurantoin or trimethoprim-sulfamethoxazole work to treat cystitis?
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Can cranberry products or topical estrogen play a role in managing urinary tract health?
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BCEN CEN
Gastrointestinal, Genitourinary, Gynecology, and Obstetrical
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