A patient arrives at the emergency department with progressive, ascending muscle weakness and areflexia. After an evaluation, Guillain-Barré syndrome is suspected. What is the most appropriate initial diagnostic test to confirm this diagnosis?
The correct answer is cerebrospinal fluid analysis which typically shows albuminocytological dissociation (high protein level with normal white cell count) which is notably characteristic of Guillain-Barré syndrome. Electromyography and nerve conduction studies, while useful in the diagnosis, are generally performed later to assess nerve function and not as an initial test. Full blood count and MRI are helpful in ruling out other conditions but are not specific for confirming Guillain-Barré syndrome.
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Neurological Emergencies
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