A 55-year-old male with a known history of alcohol-related liver cirrhosis presents to the emergency department with altered mental status and a distended abdomen. His vital signs show a blood pressure of 90/60 mmHg, a heart rate of 110 beats per minute, and a respiratory rate of 22 breaths per minute. On examination, you notice asterixis and a firm, tender liver edge. Based on the patient's presentation, which of the following would be the most immediate intervention to perform?
Administer lactulose to reduce ammonia levels.
Immediately start broad-spectrum antibiotics.
Perform a paracentesis to remove ascitic fluid.
Prepare the patient for emergency liver transplantation.
This patient is likely presenting with hepatic encephalopathy secondary to liver cirrhosis, as indicated by altered mental status and asterixis, a flapping tremor of the hands. A distended abdomen may indicate ascites, which is common in cirrhosis. The primary management of hepatic encephalopathy includes lactulose, which works by decreasing ammonia production through the acidification of bowel contents and conversion of ammonia to ammonium. Fluid resuscitation and antibiotics to cover potential spontaneous bacterial peritonitis can be considered but are not the immediate intervention for altered mental status due to hepatic encephalopathy.
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Gastrointestinal, Genitourinary, Gynecology, and Obstetrical
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